USSR: Down Georgia way

Another way to break down

hen yeast secretory proteins are improperly folded, the ER quality control system directs them into the HRD/DER pathway, which targets the proteins for degradation. Blocking the HRD/DER pathway, however, does not completely stop degradation, implying that there must be an alternative way to destroy misfolded secretory proteins. Haynes et al., reporting on page 91, have now characterized that pa...

Models all the way down

When I entered graduate school in 1984, there was scant serious work in history or philosophy of the modern earth sciences. Excellent scholars had written on Darwin, Lyell and nineteenth century geology, and some of that work heeded earth science qua earth science, but much of it attended to geology only as something that helped to lay the groundwork for an advance in biology: Darwin’s theory o...

Leading the Way in Preventing Childhood Obesity in Georgia.

s. http://georgiashape.org/sites/default/files/u21/PHR%20Abstract%20Book.pdf. Published 2015. Accessed

Dark matter cores all the way down

We use high-resolution simulations of isolated dwarf galaxies to study the physics of dark matter cusp-core transformations at the edge of galaxy formation: M200 = 107–109 M . We work at a resolution (∼4 pcminimumcell size;∼250M per particle) atwhich the impact from individual supernovae explosions can be resolved, becoming insensitive to even large changes in our numerical ‘sub-grid’ parameter...

Foreword: Federalism All the Way Down